Insulin resistance in obese children

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Insulin resistance in obese children and adolescents.

OBJECTIVE To evaluate the presence of insulin resistance and its association with other metabolic abnormalities in obese children and adolescents. METHODS Retrospective study of 220 children and adolescents aged 5-14 years. Anthropometric measurements were performed (weight, height, and waist circumference) and clinical (gender, age, pubertal stage, and degree of obesity) and biochemical (glu...

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Whole-Body and Hepatic Insulin Resistance in Obese Children

BACKGROUND Insulin resistance may be assessed as whole body or hepatic. OBJECTIVE To study factors associated with both types of insulin resistance. METHODS Cross-sectional study of 182 obese children. Somatometric measurements were registered, and the following three adiposity indexes were compared: BMI, waist-to-height ratio and visceral adiposity. Whole-body insulin resistance was evalua...

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Metabolic Profiles in Obese Children and Adolescents with Insulin Resistance

BACKGROUND In the past several decades, the increasing frequency of overweight and obese children and adolescents in the world has become a public health problem. It has contributed significantly to the already high tide of diabetes, cardiovascular and cerebrovascular diseases. AIM To investigate the frequency of insulin resistance and to evaluate the metabolic profile of insulin resistant an...

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Magnesium deficiency is associated with insulin resistance in obese children.

OBJECTIVE Magnesium deficiency has been associated with insulin resistance (IR) and increased risk for type 2 diabetes in adults. This study was designed to determine whether obese children exhibit serum or dietary magnesium deficiency and its potential association with IR. RESEARCH DESIGN AND METHODS We studied 24 obese nondiabetic children (BMI > or =85th percentile) and 24 sex- and puberty...

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Insulin Resistance during Puberty in Non-obese Japanese Children

We examined whether non-obese Japanese children without diabetes exhibited insulin resistance during puberty. The study subjects were 201 Japanese school students, consisting 95 males and 106 females, aged 11.5 ± 2.6 yr. None of the subjects were obese, with the mean percent of overweight being 0.7 ± 10.5%, or had diabetes at the time of the study. Overnight fasting plasma values of insulin (FI...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1978

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197802000-00073